Fruit Bats’ Sugar Metabolism May Inspire New Diabetes Treatments

Fruit bats are fascinating animals that have evolved to eat large amounts of sugar without suffering from diabetes. Their unique metabolism could offer new insights into how to prevent and treat this chronic disease affecting millions worldwide.

How Fruit Bats Eat Sugar and Stay Healthy

(Photo : GREG WOOD/AFP via Getty Images)

Fruit bats, also known as flying foxes, are the largest bats in the world. They feed mainly on fruits, nectar, and pollen, which are rich in sugar.

They can consume up to twice their body weight in sugary fruit daily. This would be fatal for most mammals, as high levels of sugar in the blood can damage the organs and cause diabetes.

However, fruit bats have developed particular adaptations that allow them to process sugar efficiently and effectively.

Scientists from the University of California, San Francisco, have been studying these adaptations and have discovered some remarkable features in the fruit bats' physiology. One of these features is the ability to regulate the production and secretion of insulin, the hormone that controls blood sugar levels.

Unlike humans, who secrete insulin in response to sugar intake, fruit bats secrete insulin before they eat, preparing their bodies for the sugar rush. This prevents the blood sugar levels from spiking too high and causing damage.

Another feature is the ability to use sugar as a source of energy and heat. Fruit bats have a high metabolic rate and a low body temperature, which means they need a lot of energy to maintain their functions.

Sugar provides them a quick and easy fuel to burn off rapidly. This also helps them to keep warm in cold environments, as sugar generates heat when metabolized.

Also Read: Bats Decoded: Fruit Bat Chatter is More Advanced Than You Think

How Fruit Bats Can Help Us Fight Diabetes

Diabetes is a serious condition that affects more than 37 million Americans, according to the Centers for Disease Control and Prevention (CDC).

It is the eighth-leading cause of death in the United States and can lead to complications such as heart disease, kidney failure, blindness, and amputation.

Diabetes occurs when the body cannot produce or use insulin properly, resulting in high blood sugar levels. There are two main types of diabetes: type 1, which is caused by an autoimmune attack on the insulin-producing cells in the pancreas, and type 2, which is caused by insulin resistance, where the cells do not respond to insulin as they should.

The ability of fruit bats to consume high volumes of sugar without developing diabetes could revolutionize our approach to managing and preventing this chronic condition.

By studying these remarkable creatures further, scientists hope to unlock strategies to help mitigate or even prevent diabetes in humans.

For example, they could identify genes or molecules involved in the fruit bats' insulin regulation and sugar metabolism and use them as targets for new drugs or therapies.

They could also learn from the fruit bats' dietary habits and lifestyle and apply them to human nutrition and behavior. They could even use fruit bats as models for testing new treatments and interventions for diabetes.

The study of fruit bats is a breakthrough in understanding their unique metabolism and a promising avenue for diabetes research. By unraveling the secrets of these sugar-loving animals, we could find new ways to improve our own health and well-being.