According to a study on anti-aging, eating protein in moderation increases longevity.
Nutrition has long been thought to influence lifespan and health because age-related demands have an impact on metabolic health.
Recent studies have shown associations between mice's cardio-metabolic health and aging and the dietary macronutrients proteins, carbs, and lipids.
Anti-Aging Research Solves Longevity Puzzle
A study team led by Professor Yoshitaka Kondo of Waseda University examined the amount of dietary protein needed to improve metabolic health in mice as they aged.
Male mice of different ages were recruited by the researchers for their inquiry. Over two months, they fed these rats isocaloric diets with varying protein contents.
The impact of various protein diets was then assessed using measurements of skeletal muscle weight, lipid profiles of both liver and plasma and plasma amino acid profile self-organizing map (SOM) cluster analysis.
According to Kondo, the appropriate macronutrient balance for the best health results may change depending on the stage of life.
Also, according to a 2019 study that was published in the journal Biological Sciences, altering the ratio of dietary protein to carbs as mice approach old age might reduce age-specific mortality throughout life.
However, it is still unknown how much protein should be ingested to preserve the metabolic health that comes with aging.
Protein Intake Pattern
According to this new study, middle-aged mice who were fed a low-protein diet eventually developed a moderately fatty liver and had higher levels of hepatic lipids than their younger counterparts.
On the contrary, a diet containing moderate amounts of protein led to lower levels of lipids in the liver and plasma as well as blood glucose concentrations.
These findings showed that a moderate-protein diet at 25% and 35% maintained metabolic health in both young and middle-aged rats.
Researchers looked at how different-aged mice's plasma amino acid levels were affected by protein meals. Age and protein content affected the amino acid concentrations. These results were supported by SOM analysis, which also showed connections between protein consumption, hepatic triglyceride levels, and cholesterol levels.
Protein needs increase in young, reproductive mice and decreases in older, more senior animals as they mature.
Since humans have this tendency, consuming more protein may be beneficial for metabolic health. A healthy macronutrient balance may lengthen life expectancy at each stage of life.
Secrets to Longevity and an Anti-Aging Research
The study hypothesizes that a balanced protein diet may hold the key to a long, healthy life. Keeping metabolic health could be possible with moderation and a diet tailored to age.
The ground-breaking discovery that an ideal protein balance can lower age-related mortality provides a potential framework for further study.
As the understanding grows, more specific dietary advice for certain life phases may become apparent.
The study's major finding is that a balanced diet with a modest protein intake may hold the secret to living a long, healthy life.
Additionally, lifestyle aspects like nutrition, exercise, and sleep need to be thoroughly researched because they have a considerable impact on longevity and healthspan.
However, aging is a multifaceted process involving interdependent biological systems, thus finding a single cure for aging is improbable. Instead, anti-aging research is anticipated to lead to a variety of therapies that might be used to lengthen lifespan and improve health, Earth.com reported.
The study done by Kondo and his team was recently published in the journal GeroScience.
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