Mixed-Breed Dogs at Equal Risk of Genetic disorders as Pure-Breeds

Mixed-breed dogs don't have the genetic edge over dogs that are purebred, a new study has found. The research challenges the idea that purebred dogs have a high risk of developing genetic diseases.

The study provides vital information about the risk of genetic diseases in dogs, which could help vets diagnose and treat the condition.

"Overall, the study showed that the prevalence of these genetic disorders among purebred and mixed-breed dogs depends on the specific condition," said Anita Oberbauer, animal physiologist professor and chair of the Department of Animal Science at UC Davis, and lead author of the study.

The study was based on data obtained from 90,000 purebred and mixed-breed dogs. All dogs in the study were examined at UC Davis' veterinary medical teaching hospital between 1995 and 2010.

There were more than 27,200 dogs in the study group that were diagnosed with various genetic disorders such as cancers, heart diseases, liver conditions, cataract and various orthopedic problems.

For this study, researchers selected 24 genetic disorders that were diagnosed early and were severe enough for the dog owners to consult a veterinarian.

Researchers found that the prevalence of at least 13 of the 24 disorders was roughly the same for both pure- and mixed-breed dogs. One disorder was more common among mixed-breeds, whereas 10 were common in purebred dogs.

The study also found that dogs that share a common ancestor - sharing the lineage - have higher chances of developing certain genetic disorders. For example, Bernese mountain dog, Newfoundland, mastiff and Rottweiler - that have mastiff-like lineage - were among the top five breeds that have higher odds of elbow dysplasia.

"Results from this study give us insight into how dog breeding practices might be modified to reduce the prevalence of certain genetic disorders," Oberbauer said in a news release.

The study is published in the Journal of the American Veterinary Medical Association.